The effect of Botox when injected into horizontal lines of the forehead is striking. In most
females with thinner frontalis muscles it requires 35-40 units of Botox to flatten the horizontal
lines across the forehead. With some males, whose frontalis muscles are much thicker, it
requires up to 50 units of Botox. The procedure is relatively painless as we now use the
smallest needles available to inject the Botox.

After injection we urge patients not to recline or to exercise for two hours. The reason is we do
not want the Botox to migrate or to shift its position and be washed away in the microcirculation.
The effect of freezing the horizontal lines still allows normal expression but it eliminates the
impression of premature aging by smoothing the surface of the forehead.